2. Metabolic Disease

Metabolic Disease

Metabolic Disease

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Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-131492S
    Δ4-Dafachronic Acid-d3 98%
    Δ4-Dafachronic Acid-d3 is deuterium labeled Δ4-Dafachronic acid (HY-131492). Δ4‑Dafachronic acid is an endogenous steroid hormone, an agonist of the DAF‑12 nuclear receptor, and a key ligand for the vitamin D receptor (VDR). Δ4‑Dafachronic acid promotes the active escape developmental trajectory in Austrofundulus limnaeus embryos even under diapause‑inducing conditions. Δ4‑Dafachronic acid is suitable for research on the developmental biology.
    Δ4-Dafachronic Acid-d3
  • HY-131504A
    Valienamine 38231-86-6 98%
    Valienamine is the alpha-glucosidase inhibitor. Valienamine is the key functional component of many natural glycosidase inhibitors including the crop protectant validamycin A and the antidiabetic agent acarbose.
    Valienamine
  • HY-131515R
    Tri-Salicylic acid (Standard) 85531-17-5
    Tri-Salicylic acid (Standard) is the analytical standard of Tri-Salicylic acid (HY-131515). This product is intended for research and analytical applications. Tri-Salicylic acid (Compound III) is a compound with similar properties to salicylic acid. Tri-Salicylic acid can be used in the research of inflammation, obesity, diabetes, and cardiovascular disease.
    Tri-Salicylic acid (Standard)
  • HY-131760A
    2'-NH2-ATP tetrasodium 98%
    2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate) tetrasodium, an adenosine derivative, is a weak competitive inhibitor of ATP, with a Ki of 2.3 mM. 2'-NH2-ATP can be used in nucleic acid labeling.
    2'-NH2-ATP tetrasodium
  • HY-131789A
    2-NH2-PuTP sodium 98%
    2-NH2-PuTP (n2h6ATP) sodium, an ATP (HY-B2176) analogue, is a competitive pyruvate-stimulated adenylate cyclase inhibitor with a Ki of 1.7 mM.
    2-NH2-PuTP sodium
  • HY-131805A
    3'-O-Ac-dGTP sodium 98%
    3'-O-Ac-dGTP sodium is an acetylated derivative of the nucleoside triphosphate 2'-deoxyguanosine-5'-triphosphate.
    3'-O-Ac-dGTP sodium
  • HY-132177J
    α1-3,4 Fucosidase, Sweet almond
    α1-3,4 Fucosidase, Sweet almond is an enzyme that breaks down fucose. Fucosidosis is an autosomal recessive lysosomal storage disease caused by defective alpha-L-fucosidase with accumulation of fucose in the tissues.
    α1-3,4 Fucosidase, Sweet almond
  • HY-132177K
    α-L-Fucosidase, Bovine
    α-L-Fucosidase, Bovine (EC 3.2.1.51) is a glycosidase that hydrolyzes O- and S-glycosides, participating in the degradation of N-glycans and the degradation of glycan structures. The two substrates of α-L-Fucosidase, Bovine (EC 3.2.1.51) are α-L-fucoside and water, while its two products are L-fucose and alcohol.
    α-L-Fucosidase, Bovine
  • HY-132178B
    Cytochrome C oxidase
    Cytochrome C oxidase (complex IV) (EC 7.1.1.9) is the unique terminal oxidase of the mitochondrial respiratory chain (RC) in mammals. Cytochrome C oxidase is made up of thirteen subunits that catalyze the transfer of electrons from ferro-cytochrome c to molecular oxygen.
    Cytochrome C oxidase
  • HY-132187S
    Sphingosylphosphorylcholine-d9 2315262-28-1 99.0%
    Sphingosylphosphorylcholine-d9 is deuterium labeled Sphingosylphosphorylcholine.
    Sphingosylphosphorylcholine-d9
  • HY-132188A
    Manganese Peroxidase, Nematoloma frowardii
    Manganese Peroxidase, Nematoloma frowardii (EC 1.11.1.13) is a hemecontaining glycoprotein that is produced by ligninolytic basidiomycetes. It requires hydrogen peroxide as an oxidant. Manganese Peroxidase, Nematoloma frowardii (EC 1.11.1.13) oxidizes Mn2+ to Mn3+. Mn3+ oxidizes phenolic rings to phenoxy radicals which results in the decomposition of various compounds.
    Manganese Peroxidase, Nematoloma frowardii
  • HY-132397S
    Phenylephrone-d3 hydrochloride 1246819-29-3 98%
    Phenylephrone-d3 (hydrochloride) is a deuterium labeled Phenylephrone hydrochloride. Phenylephrone hydrochloride can be used for the phenylephrone chemical delivery systems as safe and effective mydriatic agents.
    Phenylephrone-d3 hydrochloride
  • HY-132586C
    Viltolarsen sodium scrambled negative control 98%
    Viltolarsen sodium scrambled negative control is the sequence scrambled negative control of Viltolarsen sodium.
    Viltolarsen sodium scrambled negative control
  • HY-132586D
    FAM labled Viltolarsen sodium 98%
    FAM labled Viltolarsen sodiumis a FAM labled Viltolarsen sodium.
    FAM labled Viltolarsen sodium
  • HY-132586E
    Cy3 labled Viltolarsen sodium 98%
    Cy3 labled Viltolarsen sodium is a Cy3 labled Viltolarsen sodium.
    Cy3 labled Viltolarsen sodium
  • HY-132591C
    Inclisiran sodium scrambled negative control 98%
    Inclisiran sodium scrambled negative control is the sequence scrambled negative control of Inclisiran sodium.
    Inclisiran sodium scrambled negative control
  • HY-132591D
    FAM labled Inclisiran sodium 98%
    FAM labled Inclisiran sodiumis a FAM labled Inclisiran sodium.
    FAM labled Inclisiran sodium
  • HY-132591E
    Cy3 labled Inclisiran sodium 98%
    Cy3 labled Inclisiran sodium is a Cy3 labled Inclisiran sodium.
    Cy3 labled Inclisiran sodium
  • HY-132592A
    Suvodirsen sodium 2142024-01-7
    Suvodirsen sodium induces exon 51 skipping and has the potential for study Duchenne muscular dystrophy (DMD).
    Suvodirsen sodium
  • HY-132592C
    Suvodirsen sodium scrambled negative control 98%
    Suvodirsen sodium scrambled negative control is the sequence scrambled negative control of Suvodirsen sodium.
    Suvodirsen sodium scrambled negative control
Cat. No. Product Name / Synonyms Application Reactivity